allergies, treat and prevent them
In view of the spring, here is the latest research trends
More and more people are suffering allergies.
itching, sneezing, watery eyes as well as breathing difficulties and even asthma make it a "hell" the lives of millions of allergy sufferers arrival of Spring.
To learn more and to know the latest trends in research in this field, we place a few questions to Dr. Antonio Arrighi, a pediatrician and expert in Homotoxicology.
He feels that allergies are increasingly common. This information is true?
"Yes Undoubtedly, the allergic disease in the last 50 years has had a dramatic increase in incidence. It is estimated that between 20% and 30% of the population in industrialized countries suffer. The most common allergies are: eczema atopic eczema, allergic rhinitis, allergic asthma. In recent times food allergies are also grown significantly. "
What you believe to be the cause of allergic disease and because their incidence in recent years has grown so?
"allergy has a multifactorial etiology. There is a genetic predisposition in some individuals (the probability of developing an allergy if neither parent is allergic is 15%, the percentage rises to 50% if one parent is allergic and get 80% if both are allergic) but this is not enough to trigger an allergic phenomenon. And 'necessary that the subject is exposed to environmental allergens and the environment in recent years has been "tinted" to allergens, we think the carpet , environmental pollution, a more refined foods, etc.. Finally, the case now considered to be perhaps the most important for the development of a allergy, is the alteration of the immune system. By this we mean that the sufferer the immune system is like crazy, too much a part of it has developed to the detriment of another, and unfortunately the part that has overdeveloped is the one that produces IgE antibodies responsible for the sensitization and the subsequent demonstration allergic.
Because these individuals have developed this part of the immune system too?
"This is the real question to understand the reason of allergy.
Today we talk about hygiene hypothesis. What do we mean? Experimental data show that during childhood if you come into contact with viruses and bacteria do not have the chance to develop properly, as it were, the good part of the immune system, by contrast, just exaggerated the other hand, that which produces IgE. In short, with a joke, wash a little 'less the hands of our children if they do not want allergy large.
We can say that allergies are an immune system disease?
"The allergic disease, like many other diseases Immune System, can be interpreted as reflecting an alteration of the so-called immune balance.
In the case of allergic disease, immune cells called Th2 (T helper 2) are hyper-expressed, that work in excess of another family of immune cells called TH1 (T helper 1).
E 'this characteristic alteration of the immune system of allergy sufferers the root cause of their illness.
As they say in Immunology, Th1/Th2 switch is the true "original sin" of allergies.
a predominant role in lymphocyte function Th (helper T lymphocytes) is played by specific biological molecules called interleukins. They may be regarded as messengers of the immune cells are able to inform and to control their function, even that of Th lymphocytes, real "conductors" immune system, which determines the fate of a positive (recovery) or negative (disease) of many pathological conditions, including allergies.
to correct abnormalities of the immune system through the use of interleukins is now one of the most fascinating areas of research and innovative molecular biology applied to medicine.
Two of these interleukins, particularly IL-12e interferon-gamma, have the ability to reduce the function of Th2 lymphocytes (hyper-expressed in the sufferer) and the production of these substances capable of triggering the pathophysiological cascade of events leading to the manifestation of allergic symptoms. These paths Ezio-pathogenic are known for some time by allergists and immunologists, but the clinical application of this knowledge has always foundered against the rock of the side effects that interleukins "allergy", IL-12 and interferon-γ, show (when ... used at high doses, those normally used to date).
What is the state of the art of research in allergy?
"In November 2009 the prestigious scientific journal Pulmonary Pharmacology & Therapeutics (Volume 22, Number 6 497-510) published the results of an interesting work conducted by the Department of Human Morphology, University of Milan on the effects of low doses of interleukin in the treatment of allergic asthma. These are extraordinary results, which open a new frontier on the possibilities of clinical use of these biological molecules, or can not be used at high doses of the drug due to serious side effects.
The results of studies of Italian researchers also designed a new scenario in the treatment of allergic diseases.
The study published in Pulmonary Pharmacology & Therapeutics has demonstrated in an animal model (mice), the therapeutic effects of very low doses of IL-12 and IFN-gamma activated according to a technique called pharmaceutical SKA (Sequential Kinetic Activation). The low doses used
nello studio hanno mostrato gli identici effetti degli alti dosaggi nel ridurre le condizioni di iper-reattività bronchiale, nel ristabilire i normali livelli di attività dei linfociti Th2, nel ridurre drasticamente la sintomatologia clinica.
L’attività antiasmatica dei bassi dosaggi è stata confermata anche dagli esami istologici e dalla conta cellulare nel fluido di lavaggio bronco-alveolare (conta degli eosinofili: uno dei più importanti indici di laboratorio per la diagnosi di allergia).
Anche le Ig-E specifiche (elemento fondamentale della manifestazione allergica) sono state significativamente inibite dal trattamento con i bassi dosaggi di interleuchine attivate.
L’elemento innovativo dello studio dei ricercatori Italian, which earned the proceedings of "Intriguing WORK" and "... The Study Suggests A NOVEL APPROACH FOR THE TREATMENT OF ASTHMA" by the referees of the Journal derives from a particular part of the discovery of association of the two interleukins, IL-12 and Interferon-γ (together show greater effects than the sum of individual effects), the other by the fact that the "scientific dream" of being able to use biological molecules such as interleukins, low-dose (the only possible to have no side effects) now becomes possible thanks to the particular procedure used in the production of pharmaceutical molecules used in the study.
It is shown that only soluzioni a bassi dosaggi di interleuchine preparate secondo il metodo SKA sono terapeuticamente efficaci tanto quanto le alte concentrazioni farmacologiche ma senza gli effetti collaterali di queste ultime.
I bassi dosaggi non attivati secondo le procedure SKA hanno viceversa mostrato un’attività biologica ed un effetto terapeutico pari a 0.
Una nuova frontiera nel campo dell’industria farmaceutica e della Biologia Molecolare sta probabilmente nascendo e i ricercatori italiani sono all’avanguardia in questo campo.
Una nuova speranza di cura per i pazienti allergici, che solo in Italia rappresentano il 20% della popolazione, sembra delinearsi all’orizzonte".
Come possono essere curate le allergie?
"Traditional medicine which offers excellent therapeutic tools, especially in acute and hyper-acute can not be ignored. I am thinking of antihistamines and steroids. However, this is basically symptomatic therapies that do not solve the underlying problem. A step in this direction was made with the use of so-called "allergy vaccines" can increase the tolerance of the individual against certain allergens. "
and homeopathy can do something?
"I'll tell you, can do much of anything. As you know Homeopathy cures the sick, not just the disease, that is trying to correct that flaw in part constitutional, in part determined by the environment, which brought the sufferer's immune system to be unbalanced and thus to respond abnormally against normally harmless substances. Today we have a drug called Engystol (1 tablet 2 times daily for 60-90 days) that carries out this task in time to rebalance the immune balance. In
Homeopathy is used to increase tolerance, as well as in Allopathy, the "allergy vaccines". Highly effective proved to be a particular combination of pollen and other allergens diluted appropriately called Allergy Plex No. 29 (20 drops 2 times a day for 60-90 days). Finally, often those with allergies show a high degree of intoxication and that's why you recommended a product called deep drainage Galium Heel (20 drops 2 times a day for 60-90 days).
Homeopathy can do something about managing allergic symptoms?
"but certainly there must always be careful evaluation by the physician who must discriminate whether to intervene with medication or with the traditional homeopathy.
on the symptoms of allergic rhinoconjunctivitis our experience leads us to recommend two particular homeopathic medicines, Luffa comp. Nasal Spray (2 sprays per nostril 4-5 times daily) and Euphrasia Eye Drops Heel (1-2 drops per eye as needed), which provided sneezing, runny nose, etc. iperlacrimazione can be effectively combated. "
Dr. Antonio Arrighi, a pediatrician and homeopath Homotoxicology
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