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diabetic macular edema: HIT 60 MILA ITALIAN
Complicanzione of diabetes can be determined with the loss of central vision. Better is to make constant checks. The European Commission approved ranibizumab

LONDON - About 60 000 people with diabetes who, in Italy, suffer from a particular complication of the disease, Oedema, swelling, macular (in the central part of the retina, the membrane of nerve ' eye), 2% in practice. It can affect both insulin - dependent, and others. In practice, two out of three diebetici after twenty years of illness, they face this eventuality.
Symptoms - It 's vision is central to decline gradually, the images are blurred and distorted. It 'so difficult to read a book, watch television, drive a car. The disturbances occur, usually in the later stage, a situation that threatens to intervene too late when the vision is now compromised. It is not however exclude the role of a control does not correct the diabetic condition, then imposes the necessary commitment to retain a valid therapeutic support.
Other causes - alcohol, smoking, high blood pressure, high concentrations of cholesterol and triglycerides in the blood, urine and protein in diabetic nephropathy.
How is the diagnosis - Indispensable are the examination of the fundus, fluoroangiography el'OCT (optical coherence tomography). The second highlights the extent of edema, by intravenous injection of a dye. The vision of the blood vessels allows the detection of any break points on leakage of blood serum in the tissues. The third calculates the thickness macular, along with the identification of spaces where fluid accumulates. It 's a non-invasive technique. But an empirical evaluation, how good is turning a blind eye. It will be easier to know if something is wrong in the other. Second test: observing a sheet of paper into squares. If the central image is distorted and blurred, it is necessary to talk to your doctor.
Therapy - Its effectiveness is closely related to the timeliness of diagnosis. This confirms the need for constant monitoring specialist. There are three types of care.
Laser - The laser focal or grid, reference therapy, can cause a burn tissue with scarring of microaneurysms and reduced sweating. Therefore does not regenerate the retina or restores lost sight, but blocks the progression of the disease.
Surgery - A choice that is being implemented in more serious cases and involves removing the vitreous (vitrectomy)
therapy with anti - VEGF - The European Commission has recently approved the specific use of ranibizumab, a monoclonal antibody, It works by blocking vascular endothelial growth factor VEGF-A, a class of proteins responsible for the increased vascular permeability, cause edema. The molecule is already in use for the form of age-related macular degeneration, with good feedback. In Italy the ranibizumab is reimbursed by the NHS for people with active neovascular age-related macular degeneration and visual acuity with best correction or more in 2 / 10.
Of this, it was discussed in Milan at a meeting sponsored by Novartis, which was attended by proff.Paolo Lanzetta, University of Udine, Stefano Piermarocchi, of the University of Padova, Monica Varano Foundation "Bietti, Maria Lucia Specchia, of 'University of Rome" Sacro Cuore "and the president of the Italian Agency for the Prevention of Blindness, Giuseppe Castronovo. In Italy there are now a million and a half 362mila visually impaired and blind.

GIAN UGO BERTI

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